For background, cf this on the basics of thermodynamics:
Thermodynamics, the entropy concept and the famous second law were first developed in analysing heat engines. Where in (a) we see the second law, in the isolated system overall increment in entropy dS must be at minimum zero, though of course the heat evolving subsys loses and the heat absorbing one gains, but dependence on temperature means the gain exceeds the loss. This of course also highlights how a system that gains heat or similar forms naturally tends to increase entropy, there being more ways for mass and energy to be distributed at micro level than before d'Q passed into it. Then in a heat engine at (b) the possibility of shaft work now leads to various possibilities for B' which both absorbs and emits energy, some as exhaust heat to D, some as shaft work, dW.
Such leads to the question of spontaneous formation of a heat engine, which is possible, e.g. a hurricane. But when such an engine shows intricate, functionally specific complex organisation, its formation by blind chance and mechanical necessity becomes maximally implausible as can be seen for the case of a piston engine (or a turbine engine) . . . here (HT, Wiki) the famous Rolls Royce Merlin V-12 used in the Spitfire, Hurricane and Mustang Fighters -- with the shaft shown sticking out:
Moreover, the associated concepts are now understood to be far broader and far more powerful, once the concept of molecules and energy states was first added (leading to statistical thermodynamics) and once, later, the conceptual link to and from Shannon's information theory was appreciated -- though this is still subject to vigorous objection in some quarters.
However, as Wikipedia acknowledged in its article on informational entropy, as at April 2011:
The relevance of this to the origin and development of life lies in the challenge to explain the origin of functionally specific complex organisation and associated information -- much of it in the form of complex digital code that operates cells and develops body plans from embryos.
Namely, as Sewell challenges, too much of what is being claimed amounts to being materially similar to a tornado video running backwards and untangling chaos into the fabric of an intact town. That becomes especially evident in the case of origin of cell based life from some claimed prebiotic soup or similar environment, but it also obtains for the claimed spontaneous origin of major body plans by blind watchmaker thesis macro-evolution.
So, the Sewell video is food for thought.
As is this Vuk Nicolic video on the DNA and RNA information "tape" controlled production of proteins in the living cell:
Protein Synthesis from Vuk Nikolic on Vimeo.
Where this illustration (HT Wiki) shows the ribosome in action:
Sewell patently has a serious point, one well worth reflecting on.
And for a first step for more cf. here on on OoL and here on on OoBPs. END